|
rs999885
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These findings indicate that the A to G base change of rs999885 may provide a protective effect on the prognosis of intermediate or advanced HCC in Chinese.
|
24416400 |
2014 |
|
rs999885
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These findings indicate that the A to G base change of rs999885 may provide a protective effect against chronic HBV infection but an increased risk for HCC in HBV persistent carriers by altering the expression of the miR-106b-25 cluster.
|
22393390 |
2012 |
|
rs9970827
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicated that rs12309362 (G > A), rs9970827 (A > G) in DHSs, and elevated expression of CEBPB were associated with a decreased risk of HCC.
|
28321907 |
2017 |
|
rs9967368
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two SNPs (rs523230 and rs9967368) in TYMS gene were significantly associated with the overall survival of HCC patients.
|
28043790 |
2017 |
|
rs9966765
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was also a significant increased risk of HCC when combining risk genotypes of these loci, i.e., rs1135519 CC and rs9966765 CC.
|
30662901 |
2018 |
|
rs9926344
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b> Our findings indicate that WWOX rs9926344 polymorphism is positively correlated with tumor recurrence and can be used as an independent prognostic marker for HCC patients after operation.
|
29675105 |
2018 |
|
rs9912300
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although we did not find any significant results in total analysis (all p>0.05), our stratified data showed that SNP rs9912300 in ACLY gene was significantly associated with overall survival of HCC patients with lower AFP level and SNP rs11871275 in ACACA gene was significantly associated with overall survival of HCC patients with higher AFP level.
|
25735330 |
2015 |
|
rs9904341
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No association between rs8073069, rs9904341 or rs1042489 in survivin gene and the risk of HCC is found in Chinese han population, but rs8073069G-rs9904341C- rs1042489T is perhaps a protective haplotype for HCC.
|
22214342 |
2012 |
|
rs988574
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study demonstrated that rs988574 of <i>ITGA1</i> and the expression of <i>ITGA5</i>, <i>ITGB5</i> and <i>ITGA2B</i> are potential independent prognostic bio-markers and therapeutic targets for HBV-related HCC patients and may be useful for the diagnosis of HBV-related HCC.
|
29100351 |
2017 |
|
rs9877457
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five polymorphisms (rs11929692, rs7644369, rs6776570, rs3821502, and rs6766459) of the EPHB1 gene and alleles of 2 polymorphisms (rs1502174 and rs9877457) were associated with HCC (p < 0.05 for both).
|
21763378 |
2011 |
|
rs985033810
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
|
rs985033810
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
|
rs975263
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our data suggest that SNP rs1990172 and SNP rs975263 in the MACC1 gene may be potential genetic markers for HCC recurrence in LT patients.
|
24465159 |
2014 |
|
rs972427414
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We assessed the influence of Ala16Val-superoxide dismutase 2, Pro198Leu-glutathione peroxidase 1, and -463G/A-myeloperoxidase genotypes (high activity for the Ala, Pro, and G alleles, respectively) on the risks of cirrhosis and hepatocellular carcinoma (HCC) in patients homozygous for the C282Y-hemochromatosis (HFE) gene mutation.
|
20673159 |
2011 |
|
rs9679162
|
|
|
0.060 |
GeneticVariation |
BEFREE |
N-acetylgalactosaminyltransferase 14 (GALNT14)-rs9679162 genotype is a prognostic predictor for chemotherapy response in advanced hepatocellular carcinoma.
|
27124048 |
2016 |
|
rs9679162
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In conclusion, this prospective study confirmed that GALN14 genotype (rs9679162) was an effective predictor for therapeutic outcome in advanced HCC patients treated by FMP chemotherapy.
|
23959947 |
2014 |
|
rs9679162
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The present study investigated the prognostic role of the N-acetylgalactosaminyltransferase 14 (<i>GALNT14</i>)-rs9679162 genotype, an effective therapeutic response predictor for hepatocellular carcinoma in patients with cholangiocarcinoma receiving surgical resection.
|
28588705 |
2017 |
|
rs9679162
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Combinations of single nucleotide polymorphisms WWOX-rs13338697, GALNT14-rs9679162 and rs6025211 effectively stratify outcomes of chemotherapy in advanced hepatocellular carcinoma.
|
28695683 |
2018 |
|
rs9679162
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A GALNT14 rs9679162 genotype-guided therapeutic strategy for advanced hepatocellular carcinoma: systemic or hepatic arterial infusion chemotherapy.
|
31611591 |
2020 |
|
rs9679162
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The rs9679162 GALNT14 genotype is potentially associated with the objective response of the first course of FMP chemotherapy in patients with far advanced hepatocellular carcinoma.
|
21635146 |
2011 |
|
rs967461896
|
|
G |
0.700 |
GeneticVariation |
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
|
rs967461896
|
|
C |
0.700 |
GeneticVariation |
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
|
rs9651118
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In summary, our findings suggested that MTHFR rs3753584, rs9651118 and rs1801133 polymorphisms may affect the risk of HCC in Chinese Han population.
|
31694048 |
2019 |
|
rs964372
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carriers with MT-1 rs8052394, rs964372, and rs8052334 A-G-T haplotype had a 2.25-fold (95 % confidence interval [CI] 1.46-3.26) risk for HCC development than the control group (A-C-T, the most common haplotype).
|
22805858 |
2013 |
|
rs9642880
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results illustrate the potential association between rs9642880 G > T and survival in HCC patients who received radiotherapy treatment.
|
29396413 |
2018 |